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DILAUDID HP 50MG/5ML
DILAUDID HP 50MG/5ML

DILAUDID (hydromorphone hydrochloride), a hydrogenated ketone of morphine, is an opioid agonist.

DILAUDID Oral Solution is supplied as 5mg/5 mL (1 mg/mL) viscous liquid.

The chemical name is 4,5α-epoxy-3-hydroxy-17-methylmorphinan-6-one hydrochloride. The molecular weight is 321.80. Its molecular formula is C17H19NO3·HCl, and it has the following chemical structure:

Instruct patients to obtain a calibrated measuring cup/syringe for administering DILAUDID Oral Solution to ensure that the dose is measured and administered accurately.

Do not use household teaspoons or tablespoons to measure DILAUDID Oral Solution using warnings AND PRECAUTIONS].

Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals [see WARNINGS AND PRECAUTIONS].
Initiate the dosing regimen for each patient individually, considering the patient's severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse [see WARNINGS AND PRECAUTIONS].
Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy. The following dosage increases with DILAUDID Oral Solution or DILAUDID Tablets and adjusts the dosage accordingly [see WARNINGS AND PRECAUTIONS].

Initial Dosage
Initiating Treatment With DILAUDID Oral Solution Or DILAUDID Tablets

Dilaudid Oral Solution

Initiate treatment with DILAUDID Oral Solution in a dosing range of one-half (2.5 mL) to two teaspoonsful (10 mL), 2.5 mg to 10 mg, every 3 to 6 hours as needed for pain.

Dilaudid Tablets

Initiate treatment with DILAUDID Tablets in a dosing range of 2 mg to 4 mg, orally, every 4 to 6 hours.
Conversion From Other Opioids To DILAUDID Oral Solution Or DILAUDID Tablets

There is inter-patient variability in the potency of opioid drugs and opioid formulations. Therefore, a conservative approach is advised when determining the total daily dosage of DILAUDID Oral Solution or DILAUDID Tablets. It is safer to underestimate a patient’s 24-hour DILAUDID dosage than to overestimate the 24-hour dosage and manage an adverse reaction due to overdose.

In general, it is safest to start DILAUDID therapy by administering half of the usual starting dose every 3 to 6 hours for DILAUDID Oral Solution; and every 4 to 6 hours for DILAUDID Tablets. The DILAUDID dose can be gradually adjusted until adequate pain relief and acceptable side effects have been achieved [see Dosage Modifications In Patients With Renal Impairment].
Conversion From DILAUDID Oral Solution Or DILAUDID Tablets To Extended-Release Hydromorphone Hydrochloride

The relative bioavailability of DILAUDID Oral Solution and DILAUDID Tablets compared to extended-release hydromorphone hydrochloride is unknown, so conversion to extended-release tablets must be accompanied by close observation for signs of excessive sedation and respiratory depression.
Dosage Modifications In Patients With Hepatic Impairment

Initiate treatment with one-fourth to one-half the usual DILAUDID starting dose depending on the degree of impairment [see Use In Specific Populations, and CLINICAL PHARMACOLOGY].
Dosage Modifications In Patients With Renal Impairment

Initiate treatment with one-fourth to one-half the usual DILAUDID starting dose depending on the degree of impairment [see Use In Specific Populations, and CLINICAL PHARMACOLOGY].
Titration And Maintenance Of Therapy

Individually titrate DILAUDID Oral Solution or DILAUDID Tablets to a dose that provides adequate analgesia and minimizes adverse reactions. Continually reevaluate patients receiving DILAUDID Oral Solution or DILAUDID Tablets to assess the maintenance of pain control and the relative incidence of adverse reactions, as well as monitoring for the development of addiction, abuse, or misuse [see WARNINGS AND PRECAUTIONS]. Frequent communication is important among the prescriber, other healthcare team members, the patient, and the caregiver/family during periods of changing analgesic requirements, including initial titration.

Suppose the pain level increases after dosage stabilization, attempt to identify the source of increased pain before increasing the DILAUDID Oral Solution or DILAUDID Tablets dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between the management of pain and opioid-related adverse reactions.

For chronic pain, doses should be administered around-the-clock. A supplemental dose of 5 to 15% of the total daily usage may be administered every two hours on an as-needed basis.

The following serious adverse reactions are described, or described in greater detail, in other sections:

  • Addiction, Abuse, and Misuse [see WARNINGS AND PRECAUTIONS]
  • Life-Threatening Respiratory Depression [see WARNINGS AND PRECAUTIONS]
  • Neonatal Opioid Withdrawal Syndrome [see WARNINGS AND PRECAUTIONS]
  • Interactions with Benzodiazepines or Other CNS Depressants [see WARNINGS AND PRECAUTIONS]
  • Adrenal Insufficiency [see WARNINGS AND PRECAUTIONS]
  • Severe Hypotension [see WARNINGS AND PRECAUTIONS]
  • Gastrointestinal Adverse Reactions [see WARNINGS AND PRECAUTIONS]
  • Seizures [see WARNINGS AND PRECAUTIONS]
  • Withdrawal [see WARNINGS AND PRECAUTIONS]

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials cannot be directly compared to rates in another drug's clinical trials. They may not reflect the rates observed in clinical practice.

Serious adverse reactions associated with DILAUDID include respiratory depression and apnea and, to a lesser degree, circulatory depression, respiratory arrest, shock, and cardiac arrest.

The most common adverse effects are lightheadedness, dizziness, sedation, nausea, vomiting, sweating, flushing, dysphoria, euphoria, dry mouth, and pruritus. These effects seem to be more prominent in ambulatory patients and those not experiencing severe pain.
Less Frequently Observed Adverse Reactions

Cardiac disorders: tachycardia, bradycardia, palpitations

Eye disorders: vision blurred, diplopia, miosis, visual impairment

Gastrointestinal disorders: constipation, ileus, diarrhea, abdominal pain

General disorders and administration site conditions: weakness, feeling abnormal, chills

Hepatobiliary disorders: biliary colic

Metabolism and nutrition disorders: decreased appetite

Musculoskeletal and connective tissue disorders: muscle rigidity

Nervous system disorders: headache, tremor, paraesthesia, nystagmus, increased intracranial pressure, syncope, taste alteration, involuntary muscle contractions, presyncope

Psychiatric disorders: agitation, mood altered, nervousness, anxiety, depression, hallucination, disorientation, insomnia, abnormal dreams

Renal and urinary disorders: urinary retention, urinary hesitation, antidiuretic effects

Respiratory, thoracic, and mediastinal disorders: bronchospasm, laryngospasm

Skin and subcutaneous tissue disorders: urticaria, rash, hyperhidrosis

Vascular disorders: flushing, hypotension, hypertension
Postmarketing Experience

The following adverse reactions have been identified during post-approval use of hydromorphone. Because these reactions are reported voluntarily from a population of uncertain size, it is impossible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Confusional state, convulsions, drowsiness, dyskinesia, dyspnea, erectile dysfunction, fatigue, hepatic enzymes, hyperalgesia, hypersensitivity reaction, and lethargy myoclonus, oropharyngeal swelling, peripheral edema, and somnolence.
Serotonin Syndrome

Cases of serotonin syndrome, a potentially life-threatening condition, have been reported during concomitant use of opioids with serotonergic drugs.
Adrenal Insufficiency

Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use.
Anaphylaxis

Anaphylaxis has been reported with ingredients contained in DILAUDID Oral Solution or DILAUDID Tablets.
Your order will be packed safely and secure and dispatched within 24 hours.
This is how your parcel will look like; the images are photographs of real shipments.
It has the size of a normal protected envelope, and it does not disclose its contents.

$ 9.3 
ADDERALL 5 MG
ADDERALL 5 MG

Adderall may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Do not use this medicine if you have used a MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine or have received a methylene blue injection.

Adderall may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

You may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.

Call your doctor right away if you have: signs of heart problems - chest pain, feeling light-headed or short of breath; signs of psychosis - paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems - unexplained wounds on your fingers or toes.

You may not be able to use Adderall if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, vascular disease, or a history of drug or alcohol addiction.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

 

You may not be able to use Adderall if you are allergic to any stimulant medicine. You may not be able to use Adderall if you have:

  • glaucoma
  • overactive thyroid
  • severe anxiety or agitation (stimulant medicine can make these symptoms worse)
  • high blood pressure
  • heart disease or coronary artery disease
  • vascular disease or hardening of the arteries
  • a history of drug or alcohol addiction

Some medicines can interact with amphetamine and dextroamphetamine and cause a serious condition called serotonin syndrome. Tell your doctor about any other medications you are using. Be sure your doctor knows if you also take opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. A symptom of serotonin syndrome may include agitation, hallucinations (hearing or seeing things that are not real), coma, fast heart rate, dizziness, sweating, feeling hot, muscle rigidity or shakiness, seizures, nausea, vomiting, or diarrhea. Stop Adderall immediately if you experience these symptoms.

 

Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have heart problems or a congenital heart defect, high blood pressure or a family history of heart disease or sudden death.

 

To make sure Adderall is safe for you, tell your doctor if you or anyone in your family has ever had:

  • Depression, anxiety, mental illness, bipolar disorder, psychosis, problems with aggression
  • Suicidal thoughts or actions
  • Motor tics (muscle twitches) or Tourette's syndrome
  • Seizures or epilepsy
  • An abnormal brain wave test (EEG)
  • Liver or kidney disease
  • Blood circulation problems in the hands or feet.

 

Taking Adderall during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

The medications in Adderall (amphetamine and dextroamphetamine) can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Adderall is not approved for use by anyone younger than 3 years old.

Get emergency medical help if you have signs of an allergic reaction to Adderall: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

 

Call your doctor at once if you have:

  • Signs of heart problems - chest pain, trouble breathing, feeling like you might pass out.
  • Signs of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia.
  • Signs of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes.
  • A seizure (convulsions).
  • Muscle twitches (tics).
  • Changes in your vision.

 

Seek medical attention right away if you have symptoms of serotonin syndrome, such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Adderall can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

 

Common Adderall side effects may include:

  • Stomach pain, loss of appetite.
  • Weight loss.
  • Mood changes, feeling nervous.
  • Fast heart rate.
  • Headache, dizziness.
  • Sleep problems (insomnia).
  • Dry mouth.

Your order will be packed safely and secure and dispatched within 24 hours.
This is how your parcel will look like, the images are photographs of real shipments.
It has the size of a normal protected envelope and it does not disclose its contents.

$ 1.05 
ADDERALL 30 MG
ADDERALL 30 MG

Adderall may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Do not use this medicine if you have used a MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine or have received a methylene blue injection.

Adderall may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

You may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.

Call your doctor right away if you have: signs of heart problems - chest pain, feeling light-headed or short of breath; signs of psychosis - paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems - unexplained wounds on your fingers or toes.

You may not be able to use Adderall if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, vascular disease, or a history of drug or alcohol addiction.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

 

You may not be able to use Adderall if you are allergic to any stimulant medicine. You may not be able to use Adderall if you have:

  • glaucoma
  • overactive thyroid
  • severe anxiety or agitation (stimulant medicine can make these symptoms worse)
  • high blood pressure
  • heart disease or coronary artery disease
  • vascular disease or hardening of the arteries
  • a history of drug or alcohol addiction

Some medicines can interact with amphetamine and dextroamphetamine and cause a serious condition called serotonin syndrome. Tell your doctor about any other medications you are using. Be sure your doctor knows if you also take opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. A symptom of serotonin syndrome may include agitation, hallucinations (hearing or seeing things that are not real), coma, fast heart rate, dizziness, sweating, feeling hot, muscle rigidity or shakiness, seizures, nausea, vomiting, or diarrhea. Stop Adderall immediately if you experience these symptoms.

 

Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have heart problems or a congenital heart defect, high blood pressure or a family history of heart disease or sudden death.

 

To make sure Adderall is safe for you, tell your doctor if you or anyone in your family has ever had:

  • Depression, anxiety, mental illness, bipolar disorder, psychosis, problems with aggression
  • Suicidal thoughts or actions
  • Motor tics (muscle twitches) or Tourette's syndrome
  • Seizures or epilepsy
  • An abnormal brain wave test (EEG)
  • Liver or kidney disease
  • Blood circulation problems in the hands or feet.

 

Taking Adderall during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

The medications in Adderall (amphetamine and dextroamphetamine) can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Adderall is not approved for use by anyone younger than 3 years old.

Get emergency medical help if you have signs of an allergic reaction to Adderall: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

 

Call your doctor at once if you have:

  • Signs of heart problems - chest pain, trouble breathing, feeling like you might pass out.
  • Signs of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia.
  • Signs of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes.
  • A seizure (convulsions).
  • Muscle twitches (tics).
  • Changes in your vision.

 

Seek medical attention right away if you have symptoms of serotonin syndrome, such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Adderall can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

 

Common Adderall side effects may include:

  • Stomach pain, loss of appetite.
  • Weight loss.
  • Mood changes, feeling nervous.
  • Fast heart rate.
  • Headache, dizziness.
  • Sleep problems (insomnia).
  • Dry mouth.

Your order will be packed safely and secure and dispatched within 24 hours.
This is how your parcel will look like, the images are photographs of real shipments.
It has the size of a normal protected envelope and it does not disclose its contents.

$ 2.5 
DESOXYN 5 MG
DESOXYN 5 MG

You should not use Desoxyn if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, or a history of drug abuse.

Desoxyn may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Do not use Desoxyn if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Desoxyn may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

You may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.

Call your doctor right away if you have: signs of heart problems--chest pain, feeling light-headed or short of breath; signs of psychosis--paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems--unexplained wounds on your fingers or toes.

You should not use Desoxyn if you are allergic to any stimulant medicine or if you have:

  • Moderate to severe high blood pressure
  • Heart disease or coronary artery disease (hardened arteries)
  • Overactive thyroid
  • Glaucoma
  • Severe anxiety, tension, or agitation (stimulant medicine can make these symptoms worse)
  • A history of drug or alcohol addiction.

Do not use Desoxyn if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, etc.

Some medicines can interact with Desoxyn and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have:

  • Heart problems or a congenital heart defect
  • High blood pressure
  • A family history of heart disease or sudden death.

To make sure this medicine is safe for you, tell your doctor if you or anyone in your family has ever had:

  • Depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions
  • Motor tics (muscle twitches) or Tourette's syndrome
  • Seizures or epilepsy
  • An abnormal brain wave test (EEG)
  • Diabetes
  • Blood circulation problems in the hands or feet.
  • When used to treat obesity, Desoxyn should be used only after other diets or medications have been tried without successful weight loss.

Taking Desoxyn during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Methamphetamine can pass into breast milk and may harm a nursing baby. It would help if you did not breast-feed while using this medicine.

Desoxyn is not approved for use by anyone younger than 6 years old. This medicine is not approved to treat obesity in a child younger than 12 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • Signs of heart problems--chest pain, trouble breathing, feeling like you might pass out
  • Signs of psychosis--hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia
  • Signs of circulation problems--numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes
  • A seizure (convulsions)
  • Muscle twitches (tics)
  • Changes in your vision.
  • Seek medical attention right away if you have serotonin syndrome symptoms, such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Desoxyn can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using Desoxyn.

Common side effects may include:

  • Headache or dizziness
  • Fast heartbeats
  • Sleep problems (insomnia)
  • Diarrhea, constipation, upset stomach
  • Tremors
  • Loss of appetite, weight loss.

Your order will be packed safely and secure and dispatched within 24 hours.
This is how your parcel will look like; the images are photographs of real shipments.
It has the size of a normal protected envelope, and it does not disclose its contents.

$ 2.12 
XENICAL 120MG
XENICAL 120 MG

The moment you take the capsules, all the active ingredients are released into your gastrointestinal tract. The essential ingredients will reduce the capacity of the cells to absorb fat from the food. This helps in the process of losing weight at a faster pace.

Common side effects

The capsules are effective in burning excess body fat. So it is obvious that side effects may be common. Patients may experience a burning sensation in the urine with mild or severe pain in the back portion of the spine.
In some cases, patients may not feel like urinating very often. It can lead to drowsiness and mood swings. Some patients who do not follow strict dose limits may also experience severe pain in the intestinal tract.
Vomiting and nausea are also the two most common side effects that you may face. Loss of appetite is also seen in many patients as the capsule kills your craving to eat more.

When to avoid taking this medicine?

In general, pregnant women should never be administered this medicine. Even if you are overweight due to pregnancy, taking Orlistat is never recommended. Before you take this medicine, it is better to consult your health expert.
Your complete body condition has to be monitored by an expert physician. The medicine is not sold without a valid prescription; you may only be able to buy it online.

Dose details

Patients who are administered this medicine should follow strict dose limits as per the physician. Young kids should never be prescribed this medicine.

When not to take Xenical 60 mg?

Holding a valid history of gallbladder issues or any pancreatic conditions should be monitored before the medicine is prescribed. If you have weak liver conditions, then avoid taking this medicine.
The medicine is also not administered for any patient who highly has diabetes.

$ 2.5 
ADDERALL 20 MG
ADDERALL 20 MG

Adderall may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Do not use this medicine if you have used a MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine or have received a methylene blue injection.

Adderall may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

You may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes.

Call your doctor right away if you have: signs of heart problems - chest pain, feeling light-headed or short of breath; signs of psychosis - paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems - unexplained wounds on your fingers or toes.

You may not be able to use Adderall if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, vascular disease, or a history of drug or alcohol addiction.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

 

You may not be able to use Adderall if you are allergic to any stimulant medicine. You may not be able to use Adderall if you have:

  • glaucoma
  • overactive thyroid
  • severe anxiety or agitation (stimulant medicine can make these symptoms worse)
  • high blood pressure
  • heart disease or coronary artery disease
  • vascular disease or hardening of the arteries
  • a history of drug or alcohol addiction

Some medicines can interact with amphetamine and dextroamphetamine and cause a serious condition called serotonin syndrome. Tell your doctor about any other medications you are using. Be sure your doctor knows if you also take opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. A symptom of serotonin syndrome may include agitation, hallucinations (hearing or seeing things that are not real), coma, fast heart rate, dizziness, sweating, feeling hot, muscle rigidity or shakiness, seizures, nausea, vomiting, or diarrhea. Stop Adderall immediately if you experience these symptoms.

 

Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have heart problems or a congenital heart defect, high blood pressure or a family history of heart disease or sudden death.

 

To make sure Adderall is safe for you, tell your doctor if you or anyone in your family has ever had:

  • Depression, anxiety, mental illness, bipolar disorder, psychosis, problems with aggression
  • Suicidal thoughts or actions
  • Motor tics (muscle twitches) or Tourette's syndrome
  • Seizures or epilepsy
  • An abnormal brain wave test (EEG)
  • Liver or kidney disease
  • Blood circulation problems in the hands or feet.

 

Taking Adderall during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

The medications in Adderall (amphetamine and dextroamphetamine) can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

Adderall is not approved for use by anyone younger than 3 years old.

Get emergency medical help if you have signs of an allergic reaction to Adderall: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

 

Call your doctor at once if you have:

  • Signs of heart problems - chest pain, trouble breathing, feeling like you might pass out.
  • Signs of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia.
  • Signs of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes.
  • A seizure (convulsions).
  • Muscle twitches (tics).
  • Changes in your vision.

 

Seek medical attention right away if you have symptoms of serotonin syndrome, such as agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Adderall can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

 

Common Adderall side effects may include:

  • Stomach pain, loss of appetite.
  • Weight loss.
  • Mood changes, feeling nervous.
  • Fast heart rate.
  • Headache, dizziness.
  • Sleep problems (insomnia).
  • Dry mouth.

Your order will be packed safely and secure and dispatched within 24 hours.
This is how your parcel will look like, the images are photographs of real shipments.
It has the size of a normal protected envelope and it does not disclose its contents.

$ 1.2 
CONCERTA 36 MG
CONCERTA 36 MG

You should not use Concerta if you have glaucoma, tics, Tourette's syndrome, severe anxiety, tension, or agitation.

Methylphenidate may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect. Call your doctor right away if you have chest pain or feel lightheaded or short of breath while taking Concerta.

Do not use Concerta if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine or have used a methylene blue injection.

Concerta may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder. Call your doctor right away if you have signs of psychosis such as paranoia, aggression, new behavior problems, or seeing or hearing things that are not real.

Do not use Concerta if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine, and others, as well as methylene blue injection.

You should not use Concerta if you are allergic to methylphenidate or if you have:

  • Glaucoma
  • A personal or family history of tics (muscle twitches) or Tourette's syndrome
  • Severe anxiety, tension, or agitation (stimulant medicine can make these symptoms worse).
  • Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have:
  • Heart problems or a congenital heart defect
  • High blood pressure
  • A family history of heart disease or sudden death.

 

To make sure Concerta is safe for you, tell your doctor if you or anyone in your family has ever had:

  • Depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions
  • Motor tics (muscle twitches) or Tourette's syndrome
  • Blood circulation problems in the hands or feet
  • Seizures or epilepsy
  • Problems with the esophagus, stomach, or intestines
  • An abnormal brain wave test (EEG)
  • A history of drug or alcohol addiction.
  • It is not known whether Concerta will harm an unborn baby.
  • Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether methylphenidate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Concerta is not approved for use by anyone younger than 6 years old.

 

Call your doctor at once if you have:

  • Signs of heart problems - chest pain, trouble breathing, feeling like you might pass out
  • Signs of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia
  • Signs of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes
  • A seizure (convulsions)
  • Muscle twitches (tics)
  • Changes in your vision
  • Penis erection that is painful or lasts 4 hours or longer (rare).

 

Concerta can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common Concerta side effects may include:

  • Mood changes, feeling nervous or irritable, sleep problems (insomnia)
  • Fast heart rate, increased blood pressure.
  • Loss of appetite, weight loss
  • Excessive sweating
  • Nausea, stomach pain
  • Headache.

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DILAUDID HP 10MG/1ML
DILAUDID HP 10MG/1ML

DILAUDID (hydromorphone hydrochloride), a hydrogenated ketone of morphine, is an opioid agonist.

DILAUDID Oral Solution is supplied as 5mg/5 mL (1 mg/mL) viscous liquid.

The chemical name is 4,5α-epoxy-3-hydroxy-17-methylmorphinan-6-one hydrochloride. The molecular weight is 321.80. Its molecular formula is C17H19NO3·HCl, and it has the following chemical structure:

Instruct patients to obtain a calibrated measuring cup/syringe for administering DILAUDID Oral Solution to ensure that the dose is measured and administered accurately.

Do not use household teaspoons or tablespoons to measure DILAUDID Oral Solution using warnings AND PRECAUTIONS].

Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals [see WARNINGS AND PRECAUTIONS].
Initiate the dosing regimen for each patient individually, considering the patient's severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse [see WARNINGS AND PRECAUTIONS].
Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy. The following dosage increases with DILAUDID Oral Solution or DILAUDID Tablets and adjusts the dosage accordingly [see WARNINGS AND PRECAUTIONS].

Initial Dosage
Initiating Treatment With DILAUDID Oral Solution Or DILAUDID Tablets

Dilaudid Oral Solution

Initiate treatment with DILAUDID Oral Solution in a dosing range of one-half (2.5 mL) to two teaspoonsful (10 mL), 2.5 mg to 10 mg, every 3 to 6 hours as needed for pain.

Dilaudid Tablets

Initiate treatment with DILAUDID Tablets in a dosing range of 2 mg to 4 mg, orally, every 4 to 6 hours.
Conversion From Other Opioids To DILAUDID Oral Solution Or DILAUDID Tablets

There is inter-patient variability in the potency of opioid drugs and opioid formulations. Therefore, a conservative approach is advised when determining the total daily dosage of DILAUDID Oral Solution or DILAUDID Tablets. It is safer to underestimate a patient’s 24-hour DILAUDID dosage than to overestimate the 24-hour dosage and manage an adverse reaction due to overdose.

In general, it is safest to start DILAUDID therapy by administering half of the usual starting dose every 3 to 6 hours for DILAUDID Oral Solution; and every 4 to 6 hours for DILAUDID Tablets. The DILAUDID dose can be gradually adjusted until adequate pain relief and acceptable side effects have been achieved [see Dosage Modifications In Patients With Renal Impairment].
Conversion From DILAUDID Oral Solution Or DILAUDID Tablets To Extended-Release Hydromorphone Hydrochloride

The relative bioavailability of DILAUDID Oral Solution and DILAUDID Tablets compared to extended-release hydromorphone hydrochloride is unknown, so conversion to extended-release tablets must be accompanied by close observation for signs of excessive sedation and respiratory depression.
Dosage Modifications In Patients With Hepatic Impairment

Initiate treatment with one-fourth to one-half the usual DILAUDID starting dose depending on the degree of impairment [see Use In Specific Populations, and CLINICAL PHARMACOLOGY].
Dosage Modifications In Patients With Renal Impairment

Initiate treatment with one-fourth to one-half the usual DILAUDID starting dose depending on the degree of impairment [see Use In Specific Populations, and CLINICAL PHARMACOLOGY].
Titration And Maintenance Of Therapy

Individually titrate DILAUDID Oral Solution or DILAUDID Tablets to a dose that provides adequate analgesia and minimizes adverse reactions. Continually reevaluate patients receiving DILAUDID Oral Solution or DILAUDID Tablets to assess the maintenance of pain control and the relative incidence of adverse reactions, as well as monitoring for the development of addiction, abuse, or misuse [see WARNINGS AND PRECAUTIONS]. Frequent communication is important among the prescriber, other healthcare team members, the patient, and the caregiver/family during periods of changing analgesic requirements, including initial titration.

Suppose the pain level increases after dosage stabilization, attempt to identify the source of increased pain before increasing the DILAUDID Oral Solution or DILAUDID Tablets dosage. If unacceptable opioid-related adverse reactions are observed, consider reducing the dosage. Adjust the dosage to obtain an appropriate balance between the management of pain and opioid-related adverse reactions.

For chronic pain, doses should be administered around-the-clock. A supplemental dose of 5 to 15% of the total daily usage may be administered every two hours on an as-needed basis.

The following serious adverse reactions are described, or described in greater detail, in other sections:

  • Addiction, Abuse, and Misuse [see WARNINGS AND PRECAUTIONS]
  • Life-Threatening Respiratory Depression [see WARNINGS AND PRECAUTIONS]
  • Neonatal Opioid Withdrawal Syndrome [see WARNINGS AND PRECAUTIONS]
  • Interactions with Benzodiazepines or Other CNS Depressants [see WARNINGS AND PRECAUTIONS]
  • Adrenal Insufficiency [see WARNINGS AND PRECAUTIONS]
  • Severe Hypotension [see WARNINGS AND PRECAUTIONS]
  • Gastrointestinal Adverse Reactions [see WARNINGS AND PRECAUTIONS]
  • Seizures [see WARNINGS AND PRECAUTIONS]
  • Withdrawal [see WARNINGS AND PRECAUTIONS]

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials cannot be directly compared to rates in another drug's clinical trials. They may not reflect the rates observed in clinical practice.

Serious adverse reactions associated with DILAUDID include respiratory depression and apnea and, to a lesser degree, circulatory depression, respiratory arrest, shock, and cardiac arrest.

The most common adverse effects are lightheadedness, dizziness, sedation, nausea, vomiting, sweating, flushing, dysphoria, euphoria, dry mouth, and pruritus. These effects seem to be more prominent in ambulatory patients and those not experiencing severe pain.
Less Frequently Observed Adverse Reactions

Cardiac disorders: tachycardia, bradycardia, palpitations

Eye disorders: vision blurred, diplopia, miosis, visual impairment

Gastrointestinal disorders: constipation, ileus, diarrhea, abdominal pain

General disorders and administration site conditions: weakness, feeling abnormal, chills

Hepatobiliary disorders: biliary colic

Metabolism and nutrition disorders: decreased appetite

Musculoskeletal and connective tissue disorders: muscle rigidity

Nervous system disorders: headache, tremor, paraesthesia, nystagmus, increased intracranial pressure, syncope, taste alteration, involuntary muscle contractions, presyncope

Psychiatric disorders: agitation, mood altered, nervousness, anxiety, depression, hallucination, disorientation, insomnia, abnormal dreams

Renal and urinary disorders: urinary retention, urinary hesitation, antidiuretic effects

Respiratory, thoracic, and mediastinal disorders: bronchospasm, laryngospasm

Skin and subcutaneous tissue disorders: urticaria, rash, hyperhidrosis

Vascular disorders: flushing, hypotension, hypertension
Postmarketing Experience

The following adverse reactions have been identified during post-approval use of hydromorphone. Because these reactions are reported voluntarily from a population of uncertain size, it is impossible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Confusional state, convulsions, drowsiness, dyskinesia, dyspnea, erectile dysfunction, fatigue, hepatic enzymes, hyperalgesia, hypersensitivity reaction, and lethargy myoclonus, oropharyngeal swelling, peripheral edema, and somnolence.
Serotonin Syndrome

Cases of serotonin syndrome, a potentially life-threatening condition, have been reported during concomitant use of opioids with serotonergic drugs.
Adrenal Insufficiency

Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use.
Anaphylaxis

Anaphylaxis has been reported with ingredients contained in DILAUDID Oral Solution or DILAUDID Tablets.
Your order will be packed safely and secure and dispatched within 24 hours.
This is how your parcel will look like; the images are photographs of real shipments.
It has the size of a normal protected envelope, and it does not disclose its contents.

$ 3.5